Mark Twain had a complex and ultimately troubled relationship with Isabel Lyon (1863-1958), who served as his secretary in his later years. It eventually resulted in her dismissal in April 1909 and Twain’s writing of the infamous Ashcroft-Lyon Manuscript, a 429-page diatribe that attacked Lyon and her husband, Ralph Ashcroft, who with Lyon had for a time controlled all of the author’s business matters. Many years before Lyon would live near Mark Twain in Redding, Connecticut, she had resided with her mother, Georgiana Van Kleek Lyon (1838-1926), in Farmington. In the early 1890s, the widowed Georgiana lived with her children, Isabel, Louise and Charles, at Oldagate, an historic house at 148 Main Street in Farmington. Louise married Jesse Moore, a bond salesman with Richter & Co. in Hartford, who joined the Lyon household. The family engaged Henry H. Mason to build two houses across the street from Oldgate, which they moved into in 1893. The Moores and their new baby occupied 141 Main Street. Isabel built a house for herself and her mother, Georgiana, next door at 143 Main Street. Charles H. Lyon, Jr., Isabel’s brother, died in 1893, probably a suicide.